Active substance: Norfloxacin
Centers for Disease Control study found patients treated with fluoroquinolones experienced adverse events severe enough to lead to an emergency department visit more frequently than those treated with cephalosporins or macrolides, but less frequently than those treated with penicillins, clindamycin, sulfonamides, or vancomycin.
Among these, tendon problems and exacerbation of the symptoms of the neurological disorder myasthenia gravis are the subject of "black box" warnings in the United States. Younger people typically experience good recovery, but permanent disability is possible, and is more likely in older patients.
Simultaneous use of corticosteroids is present in almost one-third of quinolone-associated tendon rupture.
Fluoroquinoline treatment is associated with risk that is similar to or less than that associated with broad spectrum cephalosporins. Therefore, cyclosporine serum levels should be monitored and appropriate cyclosporine dosage adjustments made when these drugs are used concomitantly.
Medications Some quinolones exert an inhibitory effect on the cytochrome P-450 system, thereby reducing theophylline clearance and increasing theophylline blood levels. These crystals cannot be seen by the naked eye.
Drinking plenty of liquid can help prevent this occurring. If you develop severe and persistent diarrhoea whilst you are taking your tablets or after stopping your tablets you should consult your doctor.
Other medicines and Norfloxacin 400 mg Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.The concomitant crataegus of quinolones including norfloxacin with unfinished calgary in elderly volunteers 65 various, contending antibiotic use not rehabilitative against C.
You must tell your doctor if you are taking other medicines that can alter your heart rhythm: medicines that belong to the group of anti-arrhythmics e.
Multivitamins, products containing iron or zinc, antacids or sucralfate should not be taken at the same time as this medicine. This medicine should be taken either 2 hours before or at least 4 hours after such products.
Pregnancy, breast-feeding and fertility If you are pregnant, planning a family or breast-feeding, tell your doctor before taking this medicine, as it is not recommended for use under these conditions.
How to take Norfloxacin 400 mg Always take your medicine exactly as your doctor or Pharmacist has told you. You should check with your doctor or pharmacist if you are not sure.
The usual dose in adults is 1 film-coated tablet 400 mg norfloxacin twice daily.
The recommended dose is 1 film-coated tablet 400 mg norfloxacin once daily.