Active substance: Doxycycline
The patient in this case was able to return to his normal daily living, completed his course of antibiotics, had the sutures removed from the wound on a subsequent visit, and displayed no evidence of infection.
What is your preferred empiric antibiotic therapy for a shark bite victim and why? Two things to take into account when managing a shark bite and any bite victim for that matter include the oral flora and the environment in which the injury occurred.
Bacteria are present in high concentrations in aquatic environments and differ from those encountered in land-based injuries. The absorption of doxycycline is not markedly influenced by simultaneous ingestion of food or milk.
Uncomplicated gonococcal infections in adults except anorectal infections in men: 100 mg, by mouth, twice a day for 7 days. Acute epididymo-orchitis caused by N.
Primary and secondary syphilis: 300 mg a day in divided doses for at least 10 days.
Uncomplicated urethral, endocervical, or rectal infection in adults caused by Chlamydia trachomatis: 100 mg, by mouth, twice a day for at least 7 days.
Nongonococcal urethritis caused by C. Acute epididymo-orchitis caused by C.
Children weighing 45 kg or more should receive the adult dose. Contraindications This drug is contraindicated in persons who have shown hypersensitivity to any of the tetracyclines.
This adverse reaction is more common during long-term use of the drugs, but it has been observed following repeated short-term courses. Enamel hypoplasia has also been reported.
Use of doxycycline in pediatric patients 8 years of age or less only when the potential benefits are expected to outweigh the risks in severe or life-threatening conditions e.
Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. Hypertoxin producing strains of C.
CDAD must be considered in all patients who present with diarrhea following antibiotic use. Appropriate fluid and electrolyte management, protein supplementation, antibiotic treatment of C. Intracranial hypertension IH, pseudotumor cerebri has been associated with the use of tetracyclines including Monodox.
Clinical manifestations of IH include headache, blurred vision, diplopia, and vision loss; papilledema can be found on fundoscopy.
Women of childbearing age who are overweight or have a history of IH are at greater risk for developing tetracycline associated IH. Plan your trip around 1 city and skip the rental-car expense or splurge on wheels and visit both; either way, a budget-conscious vacation that combines sun-drenched sands and urban style is well within your wallet's reach with a little advance planning.
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